
Cardiovascular anesthesia specialist — Senior Partner & Director of Cardiovascular Anesthesia at Guide Anesthesia. The only Fellow of the Heart Rhythm Society among anesthesia providers worldwide.
About
An unparalleled depth of expertise at the intersection of cardiac electrophysiology, complex hemodynamics, and anesthesiology.
Jacob D. Hantla, DNAP, CRNA, FHRS is a Doctor of Nurse Anesthesia Practice (DNAP) and board-certified nurse anesthesiologist with 14+ years of subspecialty focus in electrophysiology, cardiovascular, and vascular anesthesia. He leads one of the most specialized cardiac EP anesthesia teams in the United States.
As Senior Partner and Director of Cardiovascular Anesthesia at Guide, Dr. Hantla oversees clinical operations across more than 10 cardiovascular ASC and hospital sites in the Phoenix metro area and leads the CV division of Guide Anesthesia in multiple states across the country.
He consults and speaks regularly for Abbott Laboratories, Biosense Webster / J&J MedTech, and Abiomed on complex hemodynamics, cardiac electrophysiology, and anesthesia, and has served as an expert advisor to the Arizona State Board of Nursing and national CRNA associations on the role of CRNAs in transesophageal echocardiography. He is also available for independent medical-legal consultation and expert witness engagements in cardiac electrophysiology and cardiovascular anesthesia.
Outside of anesthesia, Jacob is a pastor/elder at Grace Bible Church in Tempe, Arizona, a task he has been privileged to serve in since 2008.
ASC Electrophysiology
Assisted in opening, staffing, training, policy development, and clinical practice management for nearly a dozen EP-focused ASCs, with hands-on involvement in 2,000+ ASC-based EP anesthesia cases since 2018.
Clinical Expertise
Cardiac Electrophysiology Anesthesia
Subspecialty expertise in anesthesia for AF ablation, cardiac device implants and explants, LAA closure, and complex ventricular tachycardia ablations.
Perioperative Transesophageal Echocardiography
Recognized authority on perioperative TEE. Advisor to the Arizona State Board of Nursing on codifying CRNA TEE scope of practice. Regular instructor across university, industry, and conference settings.
Complex Hemodynamic Management
Expert in hemodynamic management for heart failure, cardiogenic shock, low-cardiac-output states, and perioperative complications in high-acuity procedural settings.
ASC Program Development
Sought-after consultant for anesthesia program development in EP-based ambulatory surgery centers. Advisory roles for ASC portfolio growth, regulatory navigation, and clinical team development.
Medical Device Consulting
Active consulting with Abbott Laboratories, Biosense Webster / J&J MedTech, and Abiomed. National advisory board member and speakers bureau lecturer for Impella hemodynamic support.
Clinical Education & Faculty
Lecturing faculty at the University of Arizona and Midwestern University nurse anesthesia programs; keynote and special session speaker at national and state conferences. Director of Guide Academy, an internal education platform for cardiovascular anesthesiologists.
Early US Ambulatory Surgery Center Experience with Pentaspline Pulsed Field Ablation: Feasibility, Efficiency, and Safety of a 2D-ICE-and-Fluoro-Only Workflow
Heart Rhythm · HRS Scientific Sessions, April 2026
Outcomes of Left Atrial Appendage Occlusion Treatment With Amulet After Unsuccessful Watchman FLX Device: A Multicenter Observational Study
J Cardiovasc Electrophysiol. 2025;36(7):1632–1642
Case Study: Atrial Fibrillation Ablation in a Patient With Atrial Septal Closure Device Performed in an Outpatient Same Day Ambulatory Surgery Center
EP Digest · December 2024
General Anesthesia Strategies for Safe, Rapid Recovery, Fast Turnaround, and Same-Day Discharge for Complex Ablations in the EP-Specialized ASC Setting
Heart Rhythm · HRS Scientific Sessions, May 2023
Feasibility, Safety, and Efficacy of a Novel Preshaped Nitinol Esophageal Deviator — The DEFLECT GUT Study
Heart Rhythm. 2018;15(4)
Deflection and Manipulation for Esophageal Protection During Posterior Left Atrial Radiofrequency Ablations
Heart Rhythm · HRS Scientific Sessions Most Innovative Award
Speaking & Teaching
2024 / 2025 · Keynote & Presenter
AZANA Sun in the Fun Conference
Hemodynamic management & perioperative TEE
Hemodynamics, Ohm's Law, TEE workshop
2021–2023 · Live Case Presenter
Arizona Brain and Heart Symposium
Annual live case: AF ablation from the anesthesia perspective
2016–Present · Faculty
HRS Scientific Sessions
Chicago · Boston · San Francisco · San Diego · New Orleans
Faculty, lecturer, and abstract presenter
2017–2024 · Lecturer
University of Arizona & Midwestern University
Cardiac, EP, vascular & hemodynamic content · DNAP programs
2024 · Industry Lecturer
Abiomed Speakers Bureau
Perioperative Management of the Hemodynamically Unstable Patient
EP Advisory Board
2008 – Present · Regular Preacher & Teacher
Grace Bible Church
Weekly Sunday teaching · Tempe, Arizona
Education & Credentials
Doctor of Nurse Anesthesia Practice (DNAP)
Midwestern University — Glendale, Arizona
Doctoral Project: Development of a Simulation-Based TEE Competency Assessment Tool for Nurse Anesthesia Education.
Master of Science in Nurse Anesthesia
Midwestern University — Glendale, Arizona
Class Rank: First
BS Nursing & BS Bioengineering — Summa Cum Laude
Arizona State University — Tempe, Arizona
Fellow of the Heart Rhythm Society (FHRS)
Heart Rhythm Society
Active participant in the advancement of cardiac electrophysiology
2015: Certified Cardiac Device Specialist by International Board of Heart Rhythm Examiners
Recognition
2015–2016
Clinician of the Year — Statewide
Arizona Association of Nurse Anesthesiology (AZANA)
2017
"Most Innovative" Abstract Award
Heart Rhythm Society Scientific Sessions · Oral abstract on esophageal deflection for posterior left atrial ablation protection
2015–Present
Fellow, Heart Rhythm Society (FHRS)
The only FHRS-credentialed anesthesia provider worldwide
Contact
Available for clinical consultation, speaking engagements, research collaboration, industry advisory, and EP anesthesia program development.
Chandler, Arizona